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Dire Lupines were more powerful, upgraded forms of Dobermen and even the developed Lupines.
In addition to the previous strengths of their lower Lupine brothers, they had unique routines and subroutines added to their Code Structure, that allowed for stealth and infiltration.
They were created by, and worked for the program known as the Effectuator to be his bodyguards, and aid in his research. Since the Effectuator worked for the Merovingian, it is possible that some of these powerful Lupines worked for him as well.